SYNTHESIS AND ANTIDEPRESSANT ACTIVITY OF SUBSTITUTED (OMEGA -AMINOALKOXY) BENZENE DERIVATIVESKIKUMOTO R; TOBE A; TONOMURA S et al.1981; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1981; VOL. 24; NO 2; PP. 145-148; BIBL. 7 REF.Article

KINETIC STUDIES ON THE SELECTIVITY OF A SYNTHETIC THROMBIN-INHIBITOR USING SYNTHETIC PEPTIDE SUBSTRATESHUIKATA A; OKAMOTO S; KIKUMOTO R et al.1979; THROMBOSIS AND HAEMOSTASIS; DEU; DA. 1979; VOL. 42; NO 3; PP. 1039-1045; BIBL. 18 REF.Article

EFFECTS OF A POTENT THROMBIN INHIBITOR, NO 407, OU DIC MODELSOHTSU K; TAMAO Y; KIKUMOTO R et al.1980; KOBE J. MED. SCI.; JPN; DA. 1980; VOL. 26; NO 1; PP. 61-71; BIBL. 20 REF.Article

THROMBIN INHIBITORS. I: ESTER DERIVATIVES OF N^ALPHA -(ARYLSULFONYL)-L-ARGININEOKAMOTO S; KINJO K; HIJIKATA A et al.1980; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1980; VOL. 23; NO 8; PP. 827-830; BIBL. 12 REF.Article

POTENT INHIBITION OF THROMBIN BY THE NEWLY SYNTHESIZED ARGININE DERIVATIVE NO. 805. THE IMPORTANCE OF STEREO-STRUCTURE OF ITS HYDROPHOBIC CARBOXAMIDE PORTIONOKAMOTO S; HIJIKATA A; KIKUMOTO R et al.1981; BIOCHEM. BIOPHYS. RES. COMMUN.; ISSN 0006-291X; USA; DA. 1981; VOL. 101; NO 2; PP. 440-446; BIBL. 11 REF.Article

Effect of argatroban, a selective thrombin inhibitor, on animal models of cerebral thrombosisTAMAO, Y; KIKUMOTO, R.Seminars in thrombosis and hemostasis. 1997, Vol 23, Num 6, pp 523-530, issn 0094-6176Article

Effect of a synthetic thrombin inhibitor MCI-9038 on experimental models of disseminated intravascular coagulation in rabbitsHARA, H; TAMAO, Y; KIKUMOTO, R et al.Thrombosis and haemostasis. 1987, Vol 57, Num 2, pp 165-170, issn 0340-6245Article

THROMBIN INHIBITORS. II: AMIDE DERIVATIVES OF NALPHA -SUBSTITUTED L-ARGININEKIKUMOTO R; TAMAO Y; OHKUBO K et al.1980; J. MED. CHEM.; ISSN 0022-2623; USA; DA. 1980; VOL. 23; NO 8; PP. 380-836; BIBL. 6 REF.Article

A NOVEL SERIES OF SYNTHETIC THROMBIN-INHIBITORS. II: RELATIONSHIPS BETWEEN STRUCTURE OF MODIFIED OM-INHIBITORS AND THROMBIN INHIBITORY EFFECTTONOMURA S; KIKUMOTO R; TAMAO Y et al.1980; KOBE J. MED. SCI.; JPN; DA. 1980; VOL. 26; NO 1; PP. 1-9; BIBL. 16 REF.Article

Inhibitory effects of tritoqualine (TRQ) on histamine release from mast cellsUMEZU, K; YUASA, S; SUDOH, A et al.Japanese journal of pharmacology. 1985, Vol 38, Num 2, pp 153-160, issn 0021-5198Article

MCl-9042, a new antiplatelet agent is a selective S₂-serotonergic receptor antagonistHARA, H; OSAKABE, M; KITAJIMA, A et al.Thrombosis and haemostasis. 1991, Vol 65, Num 4, pp 415-420, issn 0340-6245Article

Substituted (ω-aminoalkoxy)stilbene derivatives as a new class of anticonvulsantsKIKUMOTO, R; TOBE, A; FUKAMI, H et al.Journal of medicinal chemistry (Print). 1984, Vol 27, Num 5, pp 645-649, issn 0022-2623Article

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N²-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acidKIKUMOTO, R; TAMAO, Y; TEZUKA, T et al.Biochemistry (Easton). 1984, Vol 23, Num 1, pp 85-90, issn 0006-2960Article

Similarity and dissimilarity in the stereogeometry of the active sites of thrombin, trypsin, plasmin and glandular kallikreinHIJIKATA-OKUNOMIYA, A; OKAMOTO, S; KIKUMOTO, R et al.Thrombosis research. 1987, Vol 45, Num 5, pp 451-462, issn 0049-3848Article

Effect of a selective thrombin inhibitor MCl-9038 on fibrinolysis in vitro and in vivoTAMAO, Y; YAMAMOTO, T; KIKUMOTO, R et al.Thrombosis and haemostasis. 1986, Vol 56, Num 1, pp 28-34, issn 0340-6245Article